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Givinostat reduces IL-1β secretion more than 70%
which inhibits TOPK kinase activity with a median inhibitory concentration (IC50) value of 2
4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF)
InChi: InChI=1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7
N1, N11-Diethylnorspermine tetrahydrochloride 333VL-292 Givinostat reduces IL-1β secretion moreN1,N11 Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) potently induces SSAT (spermidine spermine N1 acetyltransferase) mRNA and effectively stabilizes SSAT enzyme activity. Product information CAS Number: 156886 85 0 Molecular Weight: 390. 26 Formula: C13H36Cl4N4 Chemical Name: 3,7,11,15 tetraazaheptadecane tetrahydrochloride Smiles: Cl. Cl. Cl. Cl. CCNCCCNCCCNCCCNCC InChiKey: LAWBSOKBIROCQP UHFFFAOYSA N InChi: InChI=1S C13H32N4.
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