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CAS Number: 150810-68-7
a Rho-kinase inhibitor
especially CDK1/cyclin B
NCCCCN(CC1NC2=CC=CC=C2N=1)[C@H]1CCCC2=CC=CN=C21
AV-412 free base Size:Solid 10 mg CAS Number: 150810-68-7AV 412, also known as MP 412, is a second generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR HER2 inhibitor AV 412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR HER2 expressing tumors. This agent may be active against EGFR HER2
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