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3-benzothiazol-2-yl)-1-phenylurea
Functional up-regulation of P2X3 receptors in dorsal root ganglion in a rat model of bone cancer pain
24) with pure antagonism
Oestradiol
(R)-5-Hydroxymethyl Tolterodine 2 inhibitor 1 3-benzothiazol-2-yl)-1-phenylureaDesfesoterodine, also known as PNU 200577, is a major pharmacologically active metabolite of tolterodine, a new muscarinic receptor antagonist intended for the treatment of an overactive bladder. In vitro, PNU 200577 produced a competitive and concentration dependent inhibition of carbachol induced contraction of guinea pig isolated urinary bladder strips (KB = 0. 84 nM; pA2 = 9. 14). In vivo, PNU 200577 was significantly more potent at inhibiting
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