TG 100572 Hydrochloride laconine UNC0379 is active in multiple

UNC0379 is active in multiple biochemical assays

HIF-C2 is selective for the HIF-2 isoform and has no activity to antagonize HIF-1

Chemical Name: (2S

Molecular Weight: 649

TG 100572 Hydrochloride laconine UNC0379 is active in multipleTG 100572 is a potent and selective VEGFR2 Src kinase inhibitor. TG100572 inhibits Src kinases and selected receptor tyrosine kinases, induced apoptosis of proliferating endothelial cells in vitro. TG100572 inhibits downstream molecules involved in the vascular endothelial growth factor (VEGF) signaling pathway resulted in markedly diminished levels of HSV induced angiogenesis and significantly reduced the severity of SK lesions.. Product information