Arimoclomol 0396 It induces allosteric activation of

It induces allosteric activation of AMPK and inhibition of dephosphorylation of AMPK on Thr-172

InChi: InChI=1S/C11H12N2O3S/c1-13-7-9(12-17(2

Formula: C13H16N2O3

000-fold less active at the thyroid hormone receptors TRα and TRβ compared with 3

Arimoclomol 0396 It induces allosteric activation ofArimoclomol (BRX 220 free base) is a co inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome ubiquitin system. Product information CAS Number: 289893 25 0 Molecular Weight: 313. 78 Formula: C14H20ClN3O3 Chemical Name: 3 [(1Z) chloro({[(2R) 2 hydroxy 3 (piperidin 1 yl)propoxy]imino})methyl]pyridin 1 ium 1