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10(8):1770‐1777
48(2):301-10
and FTS-DMA caused a clear decrease in the levels of K-Ras-GTP in Panc-1 cells and in U87 cells
Chemical Name: methyl 2-{8-[(naphthalen-2-yl)methyl]-4-oxo-1-phenyl-1
Arachidonic Acid Leelamide Catalog No.:M23419-C 10(8):1770‐1777Arachidonic acid leelamide is a phospholipase A2 inhibitor. Phospholipase A is a hydrolase responsible for the release of arachidonic acid from the sn2 position of phospholipids. The released arachidonic acid is then converted to mediators of inflammation by the enzymes prostaglandin synthetase and 5lipoxygenase, respectively. The inhibition of phospholipase A leads to a decrease in the release of arachidonic acid and, consequently, the inflammatory