α-Hydroxyglutaric acid Size:Contact [email protected] for quotation ClH/c1-3-15-5-4-6-16(11-15)24-21-17-12-19(27-8-7-25)20(28-10-9-26-2)13-18(17)22-14-23-21

ClH/c1-3-15-5-4-6-16(11-15)24-21-17-12-19(27-8-7-25)20(28-10-9-26-2)13-18(17)22-14-23-21

RPMI8226 cells) treatment inhibits the IL-6-induced interaction between TCF4 and β-catenin and the phosphorylation of TCF4

In MDA-MB-468 cells

SC57666 has been shown to be orally active (ED50=1

α-Hydroxyglutaric acid Size:Contact [email protected] for quotation ClH/c1-3-15-5-4-6-16(11-15)24-21-17-12-19(27-8-7-25)20(28-10-9-26-2)13-18(17)22-14-23-21Hydroxyglutaric acid (2 Hydroxyglutarate) is an hydroxy acid form of glutaric acid. Hydroxyglutaric acid is a competitive inhibitor of multiple ketoglutarate dependent dioxygenases, including histone demethylases and the TET family of 5 methlycytosine (5mC) hydroxylases. Product information CAS Number: 2889 31 8 Molecular Weight: 148. 11 Formula: C5H8O5 Chemical Name: 2 hydroxypentanedioic acid Smiles: OC(=O)CCC(O)C(O)=O InChiKey: HWXBTNAVRSUOJR