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Rosiglitazone hydrochloride - CAS# 302543-62-0 Size:10mg solid Smiles: O=C(NC1=NC=C(S1)SCCN1CCCC1)[C@@]1(C[C@H]1C1CCCCC1)C1C=CC(=CC=1)S(=O)(=O)C1CC1

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Description

Smiles: O=C(NC1=NC=C(S1)SCCN1CCCC1)[C@@]1(C[C@H]1C1CCCCC1)C1C=CC(=CC=1)S(=O)(=O)C1CC1

PubMed PMID: 26933922

9-tetrahydro-1H-carbazol-4-one

7 cells and mouse bone marrow-derived macrophages (BMMs) in a concentration-dependent manner

Rosiglitazone hydrochloride - CAS# 302543-62-0 Size:10mg solid Smiles: O=C(NC1=NC=C(S1)SCCN1CCCC1)[C@@]1(C[C@H]1C1CCCCC1)C1C=CC(=CC=1)S(=O)(=O)C1CC1Rosiglitazone hydrochloride (BRL 49653 hydrochloride) is a selective, orally active PPAR agonist with EC50s of 30 nM, 100 nM and 60 nM for PPAR1, PPAR2, and PPAR, respectively. Rosiglitazone hydrochloride binds to PPAR with a Kd of approximately 40 nM. Rosiglitazone hydrochloride is also an activator of TRPC5 (EC50=~30 M) and an inhibitor of TRPM3. Product information CAS Number: 302543 62 0 Molecular Weight: 393. 89 Formula: C18H20ClN3O3S Synonym:

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