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highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities
alleviate established l-DOPA-induced dyskinesia
A bis-Benzylidine Piperidone Targeting Proteasome Ubiquitin Receptor RPN13/ADRM1 as a Therapy for Cancer
The bioavailability following an oral dose in rats is 91%
AUY-922 - CAS# 747412-49-3 size:2mg solid highly selective and potent smallAUY 922, also known as Luminespib, NVP AUY922, VER52296, CAS No. 747412 49 3, is a derivative of 4, 5 diarylisoxazole and a third generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY 922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock
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