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InChi: InChI=1S/C17H16N4O4/c22-13-8-12(7-6-11-4-2-1-3-5-11)21-16(19-10-20-21)15(13)17(25)18-9-14(23)24/h1-5
18-triazapentacyclo[12
ACY-1215 was intraperitoneally dosed to mice consecutively for 5 days a week at 50 mg/kg dissolved in 5% dextrose in water with 10% DMSO or in combination with bortezomib (biweekly IV) 0
Chemical Name: 3-amino-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-N-(pyridin-3-yl)pyrazine-2-carboxamide
Resolvin E1 Catalog No.:M18388-C InChi: InChI=1S/C17H16N4O4/c22-13-8-12(7-6-11-4-2-1-3-5-11)21-16(19-10-20-21)15(13)17(25)18-9-14(23)24/h1-5Resolvin E1 (RvE1), a potent endogenous pro resolving mediator of inflammation, is derived from omega 3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial