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the inhibition of cell proliferation
Johnston C
regulating deubiquitination activity of USP10 and USP13 by Beclin1 provides a mechanism for Beclin1 to control the levels of p53
is a novel first in class
FG-4592 (Roxadustat) - HIF Prolyl-Hydroxylases Inhibitor. CAS# 808118-40-3 Catalog No.:M60263-10S the inhibition of cell proliferationFG 4592 (Roxadustat), CAS No. 808118 40 3, is a potent, selective and bioavailable inhibitor of hypoxia inducible factor prolyl hydroxylase. It is an analog of 2 oxoglutarate (2 OG) to inhibit HIF PH and prevent HIF turnover. While little has been published regarding the actions of this compound, similar HIF PH inhibitors suppress HIF degradation and in this way induce erythropoietin expression, promoting erythropoiesis or preventing anemia in vivo.
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