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PubMed Central PMCID: PMC3383737
which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR
In MDA-MB-231 cells
also known as INCB028050 or LY3009104
Doxorubicin Hydrochloride - CAS# 25316-40-9 Catalog No.:M10308-2 PubMed Central PMCID: PMC3383737Doxorubicin free base, also called doxorubicin, is an anthracycline antibiotic with antineoplastic activity. Approved API for cancer therapeutic use is doxorubicin HCl. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Note: Doxorubicin
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