LEE011 succinate hydrate(1:1:x) Catalog No.:M9046-2 2015 Nov 3

Name: LEE011 succinate hydrate(1:1:x) Catalog No.:M9046-2 2015 Nov 3
Brand: www.turinthailand.com
SKU: 96539867470
Price: 95.00 USD
Availability: InStock
Rating: 4.6696 (21 reviews)

SKU: 96539867470

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Description

2015 Nov 3

24)13-6-3-11(9-21-13)15(17

InChi: InChI=1S/C30H35N3O3

is a selective VEGFR1 inhibitor

LEE011 succinate hydrate(1:1:x) Catalog No.:M9046-2 2015 Nov 3LEE011 succinate hydrate is an orally available cyclin dependent kinase (CDK) inhibitor targeting cyclin D1 CDK4 and cyclin D3 CDK6 cell cycle pathway, with potential antineoplastic activity. CDK4 6 inhibitor LEE011 specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK mediated G1 S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing

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