Thalidomide-NH-amido-C2-NH2 11344 5 μM) generates endoplasmic reticulum

5 μM) generates endoplasmic reticulum (ER) stress and activated the Unfolded Protein Response (UPR) as evidenced by XBP1 mRNA splicing (2

CAS Number: 1613402-20-2

99(24):15422-7

Smiles: OC1=CC2C(CNCCC=2C(Cl)=C1O)C1C=CC(O)=CC=1

Thalidomide-NH-amido-C2-NH2 11344 5 μM) generates endoplasmic reticulumThalidomide NH amido C2 NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Product information Molecular Weight: 373. 36 Formula: C17H19N5O5 Chemical Name: N (2 aminoethyl) 2 {[2 (2,6 dioxopiperidin 3 yl) 1,3 dioxo 2,3 dihydro 1H isoindol 4 yl]amino}acetamide Smiles: NCCNC(=O)CNC1C=CC=C2C=1C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: ICFVWGDJVQUIGZ UHFFFAOYSA N