CNX-1351 - CAS# 1276105-89-5 Catalog No.:M9803-10 27R)-17-ethyl-1

27R)-17-ethyl-1

Kobe2602 may serve as a scaffold for the development of Ras inhibitors with higher potency and specificity

5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-7

is An orally bioavailable synthetic P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome

CNX-1351 - CAS# 1276105-89-5 Catalog No.:M9803-10 27R)-17-ethyl-1CNX 1351 is a selective covalent Inhibitor of PI3K. In an end point assay, CNX 1351 potently inhibited PI3K and was 20400 times less potent against , , and . CNX 1351 inhibit PI3K signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX 1351 inhibits growth of cells dependent on PI3K. CNX 1351 also inhibits PI3K signaling in vivo and bonds to p110. Product information CAS Number: 1276105 89 5 Molecular