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InChiKey: YTZALCGQUPRCGW-MXVXOLGGSA-N
but can also induce the regression of pre-existing fibrosis
Epub 2013 Feb 1
PubMed Central PMCID: PMC4109838
Valrubicin - CAS# 56124-62-0 123 InChiKey: YTZALCGQUPRCGW-MXVXOLGGSA-NValrubicin, CAS No. 56124 62 0, is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin. With a mechanism of action that appears to differ from doxorubicin, valrubicin is converted intracytoplasmically into N trifluoroacetyladriamycin, which interacts with topoisomerase II, stabilizing the complex between the enzyme and DNA; consequently, DNA replication and repair and RNA and protein synthesis are inhibited and the