orally bioavailable inhibitor that binds to the NH(2)-terminal ATP-binding pocket of Hsp90
OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CNC2=O |^1:0|
Biotechnol Bioeng
2*1H/b25-16+
Ecteinascidin 770 Size:2mg solid orally bioavailable inhibitor that bindsEcteinascidin 770 (ET 770) is a 1, 2, 3, 4 tetrahydroisoquinoline alkaloid with potent anti cancer activities; inhibits U373MG cells with an IC50 of 4. 83 nM. Product information CAS Number: 114899 80 8 Molecular Weight: 770. 85 Formula: C40H42N4O10S Synonym: Ecteinascidine 770 Et 770 Chemical Name: [(1R, 2R, 3R, 11S, 12R, 14R, 26R) 12 cyano 5, 6' dihydroxy 6, 7' dimethoxy 7, 21, 30 trimethyl 27 oxospiro[17, 19, 28 trioxa 24 thia 13, 30