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Formula: C20H16Cl2N4
a mitotic Kinesin Eg5 inhibitor
resulting in the accumulation of single- or double-strand DNA breaks
resulting in aneuploidy and formation of micronuclei
Torcetrapib 02895 Hydrochloride Formula: C20H16Cl2N4Torcetrapib, also known as CP 529,414 was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. Its development was halted in 2006 when phase III studies showed excessive all cause mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib. Torcetrapib acts (as a CETP inhibitor) by inhibiting cholesterylester transfer protein (CETP), which normally
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