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2015 Oct 26
DL-α-Hydroxyglutaric acid disodium salt 4466 2015 Oct 26IC50: N A D Hydroxyglutaric acid, an hydroxy acid formed from the hydrolysis of (R) 5 oxo 2 tetrahydrofurancarboxylic acid, is over produced in the human neurometabolic disease D hydroxyglutaric aciduria. In vitro: In humans the enzyme hydroxyacid oxoacid transhydrogenase catalyzed the formation of D hydroxyglutaric acid, while D hydroxyglutaric acid is catalyzed by 2 hydroxyglutarate synthase in bacteria. Recent study discovered heterozygous somatic
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