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HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3
Flupirtine is capable of protecting primary neurons against glutamate-induced cytotoxicity by reducing calcium ion concentrations at 1-10 mM
InChi: InChI=1S/C21H24ClFN4O3
15N2 (UTP 13C9
Piboserod hydrochloride o-PEG4-C2-N3 HIV-1 integrase inhibitor 4 isPiboserod (SB 207266) Hcl is a selective 5 HT(4) receptor antagonist. IC50 value: Target: 5 HT4 antagonistin vitro: Piboserod did not modify the basal contractions but concentration dependently antagonized the ability of 5 HT to enhance bladder strip contractions to EFS. In presence of 1 and 100 nM of piboserod, the maximal 5 HT induced potentiations were reduced to 45. 0+ 7. 9 and 38. 7+ 8. 7%, respectively . in vivo: Piboserod significantly