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P104359-WB-1-P
IHC Host Rabbit Clone type rabbit polyclonal Target Background This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes
Mutations in this gene cause Costello syndrome
as well as cell lines such as HeLa
ITCH rabbit monoclonal antibody Biochemical Reagents P104359-WB-1-PSpecification Full name ITCH rabbit monoclonal antibody Alternative names 50 l 100 l Reactivity rabbit monoclonal Applications WB Host Rabbit Clone type rabbit monoclonal Target Background This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The