You can also just focus on a player, and many spells let you choose either yourself or an opponent like Blood Pact
The return of these cards in "Journey Together" was highly anticipated, but apart from N's Zoroark ex, most of these cards did not have a noticeable impact on the meta
Julius Jumblemorph Ixalan Vona, Butcher of Magan, Tishana, Voice of Thunder, Admiral Beckett Brass, Gishath, Suns Avatar Commander 2017 Nazahn, Revered Bladesmith, Inalla, Archmage Ritualist, Mirri, Weatherlight Duelist, O-Kagachi, Vengeful Kami, Mairsil, the Pretender, Taigam, Ojutai Master Razaketh, the Foulblooded, Zur, the Enchanter (Mummys Curse), Djeru, With Eyes Open, The Locust God, Karona, False God (All the Deserts), Nicol Bolas, Neheb, the Eternal Amonkhet Oketra the True, Temmet, Vizier of Naktamun, Atogatog (Cartouches & Trials), Hapatra, Vizier of Poisons, Samut, Voice of Dissent, Rhonas the Indomitable, Hazoret the Fervent Kaladesh Block Yahenni, Undying Partisan, Nicol Bolas, Child of Alara (Five-Color Energy), Rishkar, Peema Renegade, Kari Zev, Skyship Raider, Sram, Senior Edificer Commander 2016 Breya, Etherium Shaper, Atraxa, Praetors Voice, Tymna the Weaver // Ravos, Soultender Other Commander Decks Thada Adel, Acquisitor, The Ultimate Golgari Deck, Anafenza, the Foremost (shutting down shenanigans), Momir Vig, Simic Visionary (no green creatures), Kytheon, Hero of Akros (Tribal Gideon), Tasigur, the Golden Fang
The answer to both is a resounding yes
