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ML218 hydrochloride Size:Contact [email protected] for quotation Formula: C25H28N6O

SKU: 13805099470

4.1
USD100.00 USD120.00

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Description

Formula: C25H28N6O

Gamache DA

and insulin resistance in humans

25 µM) and ERK8 (MAPK15

ML218 hydrochloride Size:Contact [email protected] for quotation Formula: C25H28N6OML218 hydrochloride is a potent, selective and orally active T type Ca2+ channels (Cav3. 1, Cav3. 2, Cav3. 3) inhibitor with IC50s of 310 nM and 270 nM for Cav3. 2 and Cav3. 3, respectively. ML218 hydrochloride inhibits the burst activity in subthalamic nucleus (STN) neurons. ML218 hydrochloride has no significant inhibition of L or N type calcium channels, KATP or hERG potassium channels. ML218 hydrochloride can penetrate the blood brain barrier.

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